PRELIMINARY PHYTOCHEMICAL AND IN VITROANTIBACTERIAL EVALUATION OF THE CRUDE PERICARP EXTRACT OF HYPHAENE THEBAICA (DOUMPALM)

PRELIMINARY PHYTOCHEMICAL AND IN VITROANTIBACTERIAL EVALUATION OF THE CRUDE PERICARP EXTRACT OF HYPHAENE THEBAICA (DOUMPALM)

 

Mohammed Shaibu Auwal1*, Umar Kyari Sandabe1, Abdulnasir Tijjani2, Fatima Abba Lawan2, Abdullahi Shuaibu3, Ismail Alh Mairiga4, Kyari Abba Sanda1, Abdulhamid Baba Njobdi5

*1Department of Veterinary Physiology, Pharmacology and Biochemistry, University of Maiduguri, Borno State, Nigeria.

2Department of Veterinary Microbiology and Parasitology, University of Maiduguri, Borno State, Nigeria.

3Department of Human Anatomy, College of Medical Sciences, University of Maiduguri, Borno State, Nigeria.

4Department of Veterinary Medicine, University of Maiduguri, Borno State, Nigeria.

5Department of Animal Health and Production, College of Agriculture Jalingo, Taraba State, Nigeria.

 

Abstract

The Preliminary phytochemical and antibacterial evaluation of crude pericarp extract of Hyphaene thebaica (doumpalm) was ascertained. The crude pericarp powder of the plant was extracted for phytochemical screening by reflux method. The phytochemical analysis of the extract revealed the presence of tannins, steroids, saponins, carbohydrates, flavonoids, terpenes and terpinoids in low and moderate concentrations. The crude pericarp extract of this plant exhibited activity on some gram positive and negative laboratory bacterial isolates such as Staphylococcus aureus, Streptococcus pyogenes, Salmonella typhi, Escherichia coli and Shigella dysenteriae and the rest of the organisms were resistant to the extract. The effect of Hyphaene thebaica aqueous pericarp extract on gram positive and negative laboratory isolates indicates broad spectrum antibacterial activity. Most of the bacterial isolates were sensitive to all the concentrations of the extract used in this research except salmonella typhi that showed resistance at the concentration of 200 mg / ml. The minimum inhibitory concentration for Staphylococcus aureus, Streptococcus pyogenes and Salmonella typhi is 25 mg / ml while that for Escherichia coli and Shigella dysenteriae is 50 mg / ml. All the laboratory isolates has a minimum bactericidal concentration of 50 mg / ml. This finding concludes that Hyphaene thebaica (doumpalm) pericarp extract have some important bioactive principles that can be used as a therapeutic agent in the inhibition of these pathogenic organisms that are incriminated in the causation of various disease in humans and animals.        

Keywords: Phytochemistry, Antibacterial, Bacteria Isolates, Crude Pericarp Extract, Hyphaene  Thebaica, 

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