AkinribidoF.A, Duru F.I.O, Yama O.E

Dept  Department of Biological Sciences, Bells University of Technology Ota, Ogun State
Dept of Anatomy,College of Medicine,University of Lagos, Idi-Araba, Lagos State



Depo-Provera inhibits follicular development and prevents ovulation in its  primary mechanism of action.The aim of this study was to evaluate and compare Effects of Depo Provera on the Morphology of  ascending colon as it is being used as a contraceptive. A single of Depo Provera contraceptive injection (150mg Medroxyprogesterone Acetate) intraperitoneally, at a dose of 75mg/ 100g body weight was given to ten matured Sprague Dawley rats daily for 10 days. Control matured Sprague Dawley rats of ten received the same amount of distilled water. After about 24hrs later, the rats were sacrificed, the rats ascending colon were assessed morphologically. Weight of treated ascending colon were compared with controls. Morphologically, Depo-Provera stimulated the ascending colon by causing increase in their weight. This shows that Depo Provera has ability to bind with other tissues causing changes in their morphology. The form and structure of any living being are not constant during the whole of its existence, but undergo a series of changes from the commencement of that existence to its end, living beings have a Development. The history of development is an account of the anatomy of a living being at the successive periods of its existence, and of the manner in which one anatomical stage passes into the next.

Keywords: Depo-Provera,Sprague Dawley Rats,Morphology, Ascending Colon

Need full length paper? Then, pay in the sum of N3000 or Dollar($) equivalent into any of the following Sunmes Integrated Accounts:UBA (1016873024), Ecobank (00750384445), (0075035139), Diamond Bank (0032742351), (0032667333). Scan and send payment voucher via: info@sunmesjournals.com and call 2347039325654 for immediate/instant deliver. Thanks

Go to top